This article is the first known to this author to evaluate curcumin for PMS, which is surprising, given curcumin’s known effects on neurotransmitter levels and inflammation, both of which are involved in the pathophysiology of PMS. In their discussion, the authors do a nice job summarizing the pathophysiology of PMS related to neurotransmitter release and inflammation, and also the studies measuring curcumin’s effect on each.